Endocrine Abstracts

Introduction: The bidirectional relationship of risk between breast cancer (BC) and thyroid cancer (TC) has been debated. Estrogens are proposed as agents implicated in the risk of developing TC promoting thyroid tumorigenesis. Therapies that reduce the effect of estrogens on their receptors in cancer cells are widely used.Objective: To correlate the use of hormonal therapy in BC with the prevalence of TC.Material and Methods: We p...

Introduction: Polyglandular Autoimmune Syndromes (PAS) are a group of diseases characterized by the association of different endocrine and non-endocrine autoimmune pathologies. Although the diagnosis of PAS is more frequent in adulthood, it can occur in pediatric age, with PAS type 3 being the most frequent.Objective: To study the prevalence and characteristics of PAS in the pediatric population of a tertiary center.Methods: Retros...

Introduction: The endocrine complications of COVID-19 remain largely unknown. Cases of central diabetes insipidus (CDI) have been reported after COVID-19, with hypophysitis being the most likely cause. COVID-19 vaccines potential adverse effects may mimetize some of these complications. We present a case of a woman who developed CDI one week after the 2 nd dose of BNT162b2 mRNA COVID-19 vaccine.Case Report: Female patient, 37 years old, with rheumatoid a...

Introduction: 17 alpha-hydroxylase deficiency (17OHD) is a rare autosomal recessive disease caused by mutations in the CYP17A gene, representing 1% of cases of Congenital Adrenal Hyperplasia (CAH). The accumulation of mineralocorticoids and the glucocorticoid effect of corticosterone induce high blood pressure (HBP) and hypokalemia.Clinical Case: A 44 year-old female reporting HBP since the age of 20 years and without chronic medication, presented at the...

Introduction: Primary bilateral macronodular adrenal hyperplasia (PBMAH) is a rare entity. Up to 1/3 of patients with incidental bilateral adrenal nodules presents biochemical evidence of hypercortisolism responsible for obesity, diabetes mellitus (DM), arterial hypertension or dyslipidemia. Its insidious course and nonspecific signs explain the underdiagnosis of this entity.Objective: To describe the case of a patient with metabolic syndrome (MS) with h...

IntroductionSARS-CoV2 infection can worsen glycemic control regardless of history of Diabetes mellitus (DM) and may precipitate new-onset diabetes (NOD). DM is also a risk factor for a greater severity of COVID-19. At-admission hyperglycemia (AH) is a known predictor of critical illness in other diseases.AimsAssess the impact of AH, regardless of the presence of DM, on the severity of COVID-19 inpatients....